Table 3.
Linear Rates of Change in Regional Thickness for AUD over AP1–2 and AP2–3 Intervals
| Region | AP1–2 | AP2–3 | Difference in β AP1–2 vs. AP2–3 | ||||
|---|---|---|---|---|---|---|---|
| β days abstinent | SE | FDR p-value | β days abstinent | SE | FDR p-value | FDR p-valuea | |
| Banks Superior Temporal Gyrus | 9.72e-04 | 3.29e-04 | .009 | 1.33e-04 | 7.53e-05 | NS | .060 |
| Caudal Anterior Cingulate | 1.10e-03 | 3.35e-03 | .004 | 1.57e-04 | 6.14e-05 | .045 | .037 |
| Caudal Middle Frontal | 1.11e-03 | 4.11e-04 | .013 | 8.99e-05 | 6.67e-05 | NS | .045 |
| Cuneus | 4.35e-04 | 2.88e-04 | NS | 1.19e-04 | 5.37e-05 | .071 | NS |
| Entorhinal | 6.89e-04 | 6.30e-04 | NS | 6.83e-05 | 1.08e-04 | NS | NS |
| Frontal Pole | 1.42e-03 | 7.50–04 | .073 | 2.35e-04 | 1.04e-04 | .064 | .040 |
| Fusiform | 1.34e-03 | 3.01e-03 | .001 | 1.06e-04 | 5.44e-04 | .101 | .044 |
| Inferior Parietal | 9.34e-04 | 2.62e-04 | .002 | 1.62e-04 | 4.88e-05 | .034 | .042 |
| Inferior Temporal | 1.24e-04 | 3.25e-04 | <.001 | 1.60e-04 | 6.89e-05 | .062 | .024 |
| Insula | 9.70e-04 | 2.47e-04 | <.001 | 1.54e-04 | 5.86e-05 | .046 | .042 |
| Isthmus Cingulate | 9.93e-04 | 2.50e-04 | <.001 | 2.09e-04 | 7.71e-05 | .042 | .068 |
| Lateral Occipital | 1.04e-03 | 2.50e-03 | <.001 | 5.56e-05 | 5.53e-05 | NS | .028 |
| Lateral Orbitofrontal | 1.38e-03 | 2.70e-03 | <.001 | 2.27e-04 | 7.66e-05 | .041 | .021 |
| Lingual | 6.05e-04 | 2.07e-04 | .011 | 3.47e-05 | 5.00e-05 | NS | .055 |
| Medial Orbitofrontal | 9.53e-04 | 3.75e-04 | .018 | 1.87e-04 | 7.49e-05 | .046 | NS |
| Middle Temporal | 1.18e-03 | 4.07e-04 | .009 | 1.89e-04 | 7.89e-05 | .057 | .031 |
| Paracentral | 1.07e-04 | 4.19e-04 | .012 | 1.21e-04 | 7.29e-05 | NS | .079 |
| Parahippocampal | 1.12e-03 | 4.07e-04 | .009 | 1.18e-03 | 4.07e-04 | .035 | NS |
| Pars Opercularis | 9.44e-04 | 3.24e-04 | <.001 | 7.86e-05 | 5.42e-05 | NS | .047 |
| Pars Orbitalis | 1.96e-03 | 3.66e-04 | <.001 | 1.72e-04 | 9.21e-05 | NS | .005 |
| Pars Triangularis | 1.97e-03 | 3.67e-04 | <.001 | 6.31e-05 | 7.42e-05 | NS | .022 |
| Pericalcarine | 5.50e-04 | 3.51e-04 | NS | 1.30e-04 | 6.92e-05 | NS | NS |
| Postcentral | 6.78e-04 | 2.81e-04 | .024 | 9.76e-05 | 5.12e-05 | NS | NS |
| Posterior Cingulate | 1.08e-03 | 2.71e-04 | <.001 | 1.56e-04 | 5.41e-05 | .035 | .030 |
| Precentral | 5.31e-04 | 4.05e-04 | NS | 1.21e-04 | 7.29e-05 | NS | NS |
| Precuneus | 9.64e-04 | 2.19e-04 | <.001 | 1.44e-04 | 4.80e-05 | .041 | .025 |
| Rostral Anterior Cingulate | 5.74e-04 | 4.62e-04 | NS | 1.68e-04 | 8.60e-05 | NS | NS |
| Rostral Middle Frontal | 1.40e-03 | 2.75e-04 | <.001 | 1.35e-04 | 5.22e-05 | .045 | .005 |
| Superior Frontal | 1.04e-03 | 3.39e-04 | .007 | 2.00e-04 | 6.41e-05 | .047 | .029 |
| Superior Parietal | 9.08e-04 | 2.90e-04 | .006 | 1.10e-04 | 5.51e-05 | .104 | .042 |
| Superior Temporal | 9.79e-04 | 3.25e-04 | .008 | 7.22e-05 | 6.49e-05 | NS | .042 |
| Supramarginal | 7.62e-04 | 2.62e-04 | .009 | 1.56e-04 | 5.42e-05 | .030 | NS |
| Temporal Pole | 1.27e-03 | 5.91e-04 | .045 | 3.82e-06 | 2.04e-06 | NS | .066 |
| Transverse Temporal | 2.82e-04 | 3.65e-04 | NS | 1.26e-06 | 1.40e-06 | NS | NS |
Note. β = slope. FDR: False Discovery Rate corrected p < .05 considered statistically significant (values between .05 and .10 are considered trends and values greater than .10 listed as not significant, NS). SE: standard error of the estimate. SE: standard error of the estimate.
a
p < .05 indicates rate of thickness change for AP1–2 is statistically greater than for AP2–3.