Table 3.
Clinical characteristics by group (N = 224)
| early-onset attempters (eo)1 N = 28 | late-onset attempters (lo)1 N = 56 | ideators (ide) N = 44 | depressed comparison group (DC) N = 58 | healthy comparison group (HC) N = 38 | p-value | post-hoc comparison | |
|---|---|---|---|---|---|---|---|
| Borderline Traits 2 | 32.81 (11.07) | 30.89 (15.90) | 32.16 (11.81) | 25.58 (9.59) | 8.86 (5.29) | <0. 001 | EO&LO&IDE&DC > HC; IDE > DC |
| Impulsivity 3 | 69.96 (10.10) | 69.61 (12.87) | 67.77 (10.27) | 65.31 (10.51) | 53.62 (8.23) | <0001 | EO&LO&IDE&DC > HC |
| Dementia Rating Scale Total Score 4 | 135.27 (4.63) | 134.72 (4.96) | 136.69 (4.45) | 136.33 (4.56) | 138.76 (2.85) | 0.002 | EO&LO < HC |
| Executive Function 5 | 6.74 (3.23) | 7.63 (3.19) | 6.24 (3.18) | 6.02 (3.59) | 5 .13 (2. 68) | 0.016 | LO > HC |
| Mental Status Exam 6 | 28.25 (1.33) | 28.18 (1.80) | 28.88 (1.30) | 28.96 (0.93) | 29.30 (0.88) | <0.001 | EO&LO < HC; LO < DC |
| Lifetime substance abuse | 17 (62.96%) | 31 (59.62%) | 23 (52.27%) | 25 (43.86%) | – | 0.272 | |
| Current substance abuse | 4 (14.81%) | 8 (15.38%) | 1 (2.27%) | 7 (12.28%) | – | 0.120 | |
| Lifetime anxiety | 24 (88.89%) | 39 (75.00%) | 35 (79.55%) | 32 (56.14%) | – | 0.006 | EO > DC |
| Current anxiety | 20 (74.07%) | 34 (65.38%) | 29 (65.91%) | 27 (47.37%) | – | 0.064 | |
| Lifetime PTSD | 16 (61.54%) | 11 (21.57%) | 10 (22.73%) | 5 (8.77%) | – | <0.001 | EO > LO&IDE&DC |
| Current PTSD | 10 (38.46%) | 5 (9.80%) | 8 (18.18%) | 4 (7.02%) | – | 0.003 | EO > LO&DC |
| Depression Severity (no suicide item) 7 | 21.15 (4.87) | 19.82 (6.18) | 19.26 (5.42) | 17.02 (4.07) | – | 0.003 | EO&LO > DC |
| Age of Depression Onset | 16.64 (7.99) | 42.61 (18.44) | 37.64 (17.45) | 42.08 (17.08) | – | <0.001 | EO < LO&IDE &DC |
| Current Suicide Ideation 8 | 16.48 (8.40) | 23.02 (7.82) | 16.20 (5.71) | – | – | <0.001 | LO > EO&IDE |
| Worst Lifetime Suicide Ideation 8 | 24.70 (6.43) | 26.31 (5.24) | 20.23 (6.99) | – | – | <0.001 | EO&LO > IDE |
| Age of First Suicide Attempt | 17.50 (6.35) | 57.16 (12.39) | – | – | – | <0.001 | EO < LO |
| Highest lethality suicide attempt | 3.11 (2.34) | 3.52 (1.83) | – | – | – | 0.390 | |
| Lifetime number of suicide attempts | 2.71 (1.74) | 1.61 (0.95) | – | – | – | <0.001 | EO > LO |
| Worst lifetime intent - planning subscore 9 | 7.50 (2.00) | 7.93 (3.20) | – | – | – | 0.546 | |
| Worst lifetime intent - total score 9 | 17.43 (4.35) | 18.68 (5.13) | – | – | – | 0.311 |
1
Attempters were separated into early and late-onset based on age of first attempt using a statistical algorithm that identified a cutoff age of 30 years old.
2
Personality Assessment Inventory – Borderline subscale (PAI-BOR).
3
Barratt Impulsiveness Scale (BIS-11).
4
Dementia Rating Scale (DRS).
5
Executive Interview (EXIT).
6
Mini-Mental State Examination (MMSE).
7
Hamilton Rating Scale for Depression – 17 Item (HRSD).
8
Scale of Suicidal Ideation (SSI).
9
Scale of Suicidal Intent (SIS).