FIGURE 1.

Activation of peroxisome proliferator‐activated receptors (PPARs). Upon activation, PPARs form heterodimers with nuclear receptors by binding to their ligands. The heterodimers then bind to peroxisome proliferator response elements (PPREs) in the promoter region, which regulates the expression of downstream target genes. These genes play crucial roles in various biological processes, such as lipid metabolism, body energy homeostasis and tumourigenesis. Figure was generated with BioRender.