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. 2024 Feb 28;23:87. doi: 10.1186/s12933-024-02158-6

Table 3.

Association between METS-IR (per 1 unit increase) and AF recurrence

Model 4 Model 5 Model 6
HR (95%CI) P value HR (95% CI) P value HR (95% CI) P value
METS-IR 1.04 (1.03–1.06) < 0.001 1.04 (1.03–1.06) < 0.001 1.04 (1.03–1.05) < 0.001
< 40.889 Reference Reference Reference
≥ 40.889 1.78 (1.54–2.07) < 0.001 1.84 (1.58–2.13) < 0.001 1.62 (1.38–1.89) < 0.001
M1 Reference Reference Reference
M2 1.32 (1.08–1.61) 0.007 1.34 (1.10–1.63) 0.004 1.26 (1.02–1.54) 0.030
M3 2.05 (1.71–2.47) < 0.001 2.14 (1.77–2.58) < 0.001 1.82 (1.50–2.22) < 0.001

AF, atrial fibrillation; CI, confidence interval; HR, hazard ratio; METS-IR, metabolic score for insulin resistance; M1: METS-IR ≤ 35.585; M2: 35.585 < METS-IR ≤ 40.863; M3: 40.863 < METS-IR

Model 4: Unadjusted

Model 5: Adjusted for age and sex

Model 6: Adjusted for age, sex, current drinking, diabetes mellitus, hyperlipidemia, coronary heart disease, duration of AF (≥ 24 months), AF type, HbA1c, left atrial diameter, platelet, CHA2DS2-VASc score