Fig. 3.

Levels of proinflammatory cytokines in the cerebrospinal fluid of WT, SOD1^G93A and FUS^R521C mice. The CSF was obtained from ALS mice at week 18. Cytokines were measured as described under Methods. All mice were subjected to the tests and training indicated in Fig. 1. Mice were treated with PS, NR ​+ ​PT, IBU or NR ​+ ​PT ​+ ​IBU as in Fig. 1A one-way analysis of variance (ANOVA) was used to make comparisons among the different treatments. Different letters indicate statistical differences, P ​< ​0.05 (n ​= ​7 in all cases).