Table 1.
Cohort demographics and clinical characteristics.
| N = 430 | |
|---|---|
| Age at stroke, mean/SD | 73.86/12.51 |
| Sex (female), n (%) | 200 (46.51) |
| Education years, mean/SD | 12.25/3.55 |
| Handedness—right, n (%) | 374 (86.98) |
| Stroke subtype, n (%) | |
| Ischemic | 362 (84.19) |
| Hemorrhagic | 65 (15.12) |
| Mixed | 3 (1.00) |
| Lesion side, n (%) | |
| Left | 153 (35.58) |
| Right | 168 (39.07) |
| Bilateral | 34 (7.91) |
| Undetermined | 75 (17.44) |
| Major vascular territory, a n (%) | |
| Anterior | 39 (9.07) |
| Middle | 177 (41.16) |
| Posterior | 59 (13.72) |
| Vertebrobasilar | 55 (12.79) |
| Multifocal | 8 (1.86) |
| Lacunar | 18 (4.19) |
| Undetermined | 74 (17.21) |
| First-ever stroke, n (%) | 292 (67.91) |
| NIHSS, b median/IQR | 5/2–10 |
| Modified Rankin Scale, c median/IQR | 1/0–2 |
| Barthel index, d median/IQR | 15/9–19 |
| Independent at admission, n (%) | 376 (87.44) |
| Dependent (care required), e n (%) | 54 (12.56) |
| Comorbidities, n (%) | |
| CCI low (0–1) | 268 (62.33) |
| CCI high (⩾2) | 162 (37.67) |
| Atrial fibrillation | 109 (25.35) |
| Hypertension | 261 (60.70) |
| Diabetes mellitus | 83 (19.30) |
| Smoking, n (%) | |
| Current | 44 (10.23) |
| Past | 34 (7.91) |
| Never | 352 (81.86) |
| Days from stroke to T1 assessment, mean (SD) | 4.38 (4.46) |
| Length of stay in hospital, mean days (SD) | 11.64 (11.44) |
IQR: interquartile range; CCI: Charlson Comorbidity Index; NIHSS: National Institute of Health Stroke Scale.
CCI scored based on ICD-10 scoring scheme through hospital records. Population data inclusive of these patients (Oxford Vascular Study) 22 indicate the predominant ethnicity (>90%) was White British.
a
Vascular supply is a crude characterization of primary territory affected.
b
NIHSS recorded for n = 320 (74%) due to not being recorded before 2014.
c
Premorbid modified Rankin Scale (mRS) reported for n = 248 (58%).
d
Barthel index was reported for n = 141 (33%).
e
Dependence was categorized as requiring formal support.