Table 2.
Sensitivity analyses.
| Exposure | Outcome | Source | Pleiotropy | Heterogeneity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Egger_intercept | SE | pval | Method | Q | Q_df | Q_pval | |||
| PM2.5 | Essential hypertension | Finn | 1.80E-03 | 3.21E-03 | 5.77E-01 | MR Egger | 66.64 | 57 | 1.79E-01 |
| Inverse variance weighted | 67.01 | 58 | 1.95E-01 | ||||||
| PM10 | 7.80E-03 | 6.51E-03 | 2.40E-01 | MR Egger | 35.43 | 31 | 2.67E-01 | ||
| Inverse variance weighted | 37.08 | 32 | 2.46E-01 | ||||||
| NO2 | 1.35E-03 | 2.77E-03 | 6.28E-01 | MR Egger | 101.49 | 88 | 1.54E-01 | ||
| Inverse variance weighted | 101.77 | 89 | 1.68E-01 | ||||||
| NOX | -1.67E-03 | 2.75E-03 | 5.46E-01 | MR Egger | 68.71 | 78 | 7.65E-01 | ||
| Inverse variance weighted | 69.08 | 79 | 7.80E-01 | ||||||
| PM2.5 | UKB | 4.23E-04 | 3.79E-04 | 2.68E-01 | MR Egger | 78.30 | 59 | 4.72E-02 | |
| Inverse variance weighted | 79.96 | 60 | 4.35E-02 | ||||||
| PM10 | 9.30E-04 | 4.70E-04 | 5.66E-02 | MR Egger | 39.41 | 31 | 1.43E-01 | ||
| Inverse variance weighted | 44.40 | 32 | 7.13E-02 | ||||||
| NO2 | 4.18E-04 | 3.27E-04 | 2.05E-01 | MR Egger | 121.60 | 86 | 6.96E-03 | ||
| Inverse variance weighted | 123.90 | 87 | 5.75E-03 | ||||||
| NOX | 5.20E-04 | 4.09E-04 | 2.08E-01 | MR Egger | 132.11 | 76 | 7.09E-05 | ||
| Inverse variance weighted | 134.91 | 77 | 5.03E-05 | ||||||