FIG. 3.

Hill-model inhibition scale vs input ligand concentration. Gain (i.e., the slope of the curve) is reasonably uniform for the N = 1 curve (no cooperativily). For N = 8, gain is quite high at the knee of the curve (in this figure, at [ion] = 10), but extremely low as we move further away from there. A worm built with N = 8 would thus only reestablish a gradient for worm fragments from near the worm's center.