Table 4. Vancomycin-resistant Enterococcus faecium bloodstream infections data, 2017–2021.

VRE BSI data	Year
	2017		2018		2019		2020		2021
Vancomycin-resistant Enterococcus bloodstream infections data
Number of VRE BSIs	154		242		241		223		246
Rate per 1,000 patient admissions	0.16		0.25		0.23		0.22		0.25
Rate per 10,000 patient days	0.23		0.33		0.30		0.30		0.33
Number of reporting hospitals	59		62		70		80		76
Antimicrobial resistance of Enterococcus faecium isolates	n	%	n	%	n	%	n	%	n	%
Ampicillin	115	100	180	100	173	100	130	98.5	142	99.3
Chloramphenicol	11	9.6	4	2.2	30	17.3	28	21.2	48	33.6
Ciprofloxacin	115	100	180	100	173	100	131	99.2	142	99.3
Daptomycina	9	7.8	11	6.1	7	4.0	4	3.0	2	1.4
Erythromycin	107	93.0	172	95.6	166	96.0	126	95.5	135	94.4
High-level gentamicin	44	38.3	76	42.2	57	32.9	35	26.5	26	18.2
Levofloxacin	115	100	178	98.9	173	100	130	98.5	142	99.3
Linezolid	0	0.0	2	1.1	3	1.7	1	0.8	1	0.7
Nitrofurantoin	51	44.3	54	30.0	66	38.2	54	40.9	112	78.3
Penicillin	115	100	180	100	173	100	131	99.2	142	99.3
Quinupristin/dalfopristin	8	7.0	18	10.0	18	10.4	7	5.3	4	2.8
Rifampicin	109	94.8	162	90.0	160	92.5	114	86.4	131	91.6
High-level streptomycin	39	33.9	60	33.3	42	24.3	29	22.0	39	27.3
Tetracycline	65	56.5	107	59.4	119	68.8	88	66.7	114	79.7
Tigecycline	0	0.0	1	0.6	0	0.0	0	0.0	0	0.0
Vancomycin	110	95.7	175	97.2	170	98.3	128	97.0	138	96.5
Total number of isolates testedb	115	N/A	180	N/A	173	N/A	132	N/A	143	N/A

Abbreviations: N/A, not applicable; VRE BSI, vancomycin-resistant Enterococcus bloodstream infection

^a Clinical and Laboratory Standards Institute (CLSI) resistance breakpoints came into effect in 2019 and was applied to all years

^b Total number reflects the number of isolates tested for each of the antibiotics listed above

Note: Aggregate mortality data reported in-text due to fluctuations in the small numbers of VRE BSI deaths reported each year