Table 2.
Association of strawberry and pelargonidin intake with global AD pathology, amyloid-β load, and phosphorylated tau tangles, among deceased participants of the Rush Memory and Aging Project
| Global AD pathology burden | Amyloid-β Load | Phosphorylated tau tangles | |
|---|---|---|---|
| N | 572 | 538 | 560 |
| A. Berry Intake (Continuous (SE, p)) | |||
| Model 1A | −0.042(0.03, 0.144) | −0.144(0.09, 0.131) | −0.114 (0.10, 0.285) |
| Model 2A | −0.012 (0.06, 0.390) | −0.091(0.09, 0.351) | −0.159 (0.11, 0.150) |
| B. Pelargonidin Intake * | |||
| Model 1B | |||
| Quartile 1 | Ref | Ref | Ref |
| Quartile 2 β (SE, p) | −0.003 (0.04, 0.938) | −0.073 (0.14, 0.596) | −0.210 (0.15, 0.176) |
| Quartile 3 β (SE, p) | −0.057 (0.04, 0.180) | −0.276 (0.14, 0.047) | −0.320 (0.16, 0.041) |
| Quartile 4 β (SE, p) | −0.083 (0.04, 0.056) | −0.293 (0.14, 0.038) | −0.309 (0.16, 0.051) |
| p for trend | 0.031 | 0.024 | 0.060 |
| Model 2B | |||
| Quartile 1 | Ref | Ref | Ref |
| Quartile 2 β (SE, p) | −0.003 (0.04, 0.948) | −0.068 (0.14, 0.619) | −0.212 (0.15, 0.170) |
| Quartile 3 β (SE, p) | −0.056 (0.04, 0.194) | −0.255 (0.14, 0.067) | −0.329 (0.16, 0.036) |
| Quartile 4 β (SE, p) | −0.081 (0.04, 0.063) | −0.265 (0.14, 0.062) | −0.321 (0.16, 0.044) |
| p for trend | 0.037 | 0.043 | 0.052 |
Linear regression models: Model 1A: adjusted for age at death, sex, education, total calories, and APOE ε4 status; Model 2A: adjusted for age at death, sex, education, total calories, APOE ε4 status, leafy green vegetables, and seafood.
*
Calorie-adjusted pelargonidin intake; Model 1B: adjusted for age at death, sex, education, APOE ε4 status, vitamin E and vitamin C; Model 2B: adjusted for age at death, sex, education, APOE ε4 status, vitamin E and vitamin C intake, and other flavonoids intake.