Fig. 6.
Analysis of the expression of osteoblast-related genes at each gentamicin (GM) concentration. The messenger RNA expression levels of runt-related transcription factor 2 (RUNX2), osterix (OSX), activating transcription factor 4 (ATF4), collagen type I (COL1A1), alkaline phosphatase (ALP), bone morphogenetic protein 2 (BMP2), and osteocalcin (OC) were evaluated and normalized by the mRNA expression level of glyceraldehyde 3-phosphate dehydrogenase (GAPDH). *p < 0.05 (Kruskal-Wallis test and Steel test), each compared to 0 μg/ml of GM.