Table 2.
Summary of 278 metabolites have significant causal effect on diabetic retinopathy.
| Phenotype | N SNP | OR | 95% CI | P | PFDR |
|---|---|---|---|---|---|
| 1-oleoylglycerophosphoethanolamine | 10 | 0.414 | 0.292–0.587 | 7.61E−07 | 6.849E−06 |
| Phenyllactate (PLA) | 20 | 0.591 | 0.418–0.836 | 0.003 | 0.026 |
| 1-stearoylglycerophosphoethanolamine | 14 | 0.636 | 0.431–0.937 | 0.022 | 0.099 |
| 1-arachidonoylglycerophosphoethanolamine | 28 | 0.656 | 0.450–0.958 | 0.029 | 0.099 |
| Erythritol | 27 | 0.691 | 0.513–0.932 | 0.015 | 0.042 |
| Pyroglutamine | 20 | 0.725 | 0.600–0.875 | 0.001 | 0.007 |
| 10-undecenoate | 30 | 0.788 | 0.667–0.932 | 0.005 | 0.042 |
| Metoprolol acid metabolite | 34 | 0.978 | 0.962–0.993 | 0.005 | 0.042 |
| Butyrylcarnitine | 51 | 1.117 | 1.023–1.219 | 0.014 | 0.062 |
| Stachydrine | 7 | 1.146 | 1.066–1.233 | 2.269E−04 | 0.002 |
| 5-oxoproline | 25 | 1.570 | 1.056–2.335 | 0.026 | 0.082 |
| Kynurenine | 44 | 1.623 | 1.042–2.526 | 0.032 | 0.097 |