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. 2024 Mar 1;14:5062. doi: 10.1038/s41598-024-52297-9

Table 2.

Different parameters for HPTLC method validation.

S. no Parameters Piperine
1 Linearity range (µg /spot; n = 12a) 2–10
2 Correlation coefficient (r2) 0.9957
3 Regression equation Y = 15.476*X + 7911
4 Calculated SD value (CATS software) 2.82
5 b Limit of detection (LOD) (ng) [3 × SD/S] 140
6 b Limit of quantification (LOQ) (ng) [10 × SD/S] 1200
7 Rf and λmax (nm) 0.63 and 340
Precision and accuracy
8 Intra-day RSD (%), n = 5 0.23
9 Inter-day RSD (%), n = 5 (day-1/day-2/day-3) 0.48
Recovery
10 Amount of standard in fruit samples (µg mg−1) containing highest Piperine 13.302
11 Amount of standard added in fruit sample (µg mg−1) 17, 34, 51
12 Amount of standard found (µg) 50.58, 67.62, 84.64
13 Recovery (%) 99.98, 100.04, 100.05

aFour concentration levels in triplicates.

bSD is the standard deviation of the blank response and S is the slope of the calibration curve.