Table 1.

Clinical characteristics of CD and CS patients and healthy subjects

	Healthy Subjects	Cushing’s Disease (CD)	Cushing's Syndrome (CS)	P
N	24	27	10
Sex F(%):M(%)	17(70.8%):8(33.3%)	21(77.7%):6(22.2%)	8(80%):2(20%)	0.73
Age mean ± SEM	44.5 ± 2.1	44.8 ± 2.6	55.7 ± 5.5	0.12
BMI mean ± SEM	24.1 ± 0.6	32.3 ± 2.1****	27.8 ± 1.0*	*0.02; ****0.0008
ACTH pg/ml (09:00 h) mean ± SEM	N.A	162.1 ± 52.7††††	17 ± 9.0	0.0001
Cortisolo ng/ml (09:00 h) mean ± SEM	N.A	165 ± 18.3	226.9 ± 26.8	0.27
24 h UFC (ULN mean and range)	N.A	2.88 (0.41–11.6)	1.53 (0.35–3.1)	0.11

*p = 0.02 and ****p = 0.0008 vs healthy subjects. ††††p < 0.0001 CD vs CS