TABLE 1.
Genotype | Tract and no. of repeat units | No. of parental colonies | No. of sibling colonies | No. lacking parental band | No. of expansionsa | No. of contractions with the following no. of repeat units lost:
|
|
---|---|---|---|---|---|---|---|
≤2 | ≥3 | ||||||
Wild type | CI90 | 4 | 182 | 3 | 0 | 0 | 3 |
rth1/rad27 | CI90 | 6 | 173 | 64 | 29 | 0 | 35 |
msh2 | CI90 | 5 | 141 | 18 | 5 | 11 | 2 |
Wild type | DI97 | 5 | 154 | 34 | 0 | 0 | 34 |
rth1/rad27 | DI97 | 17 | 493 | 358 | 29 | 0 | 329 |
msh2 | DI97 | 9 | 274 | 139 | 4 | 22 | 113 |
The tract expansions in the msh2 mutant ranged in size from 1 to 3 repeat units, while those in the rth1/rad27 mutant ranged from 1 to 40 repeat units in size.