TABLE 3.
Polarity of changes in interrupted CAG tracts
| Genotype and tract | Expansion or contraction | No. of 5′ events | No. of 3′ events |
|---|---|---|---|
| Wild type | |||
| CI90 | Expansions | NAb | NA |
| CI90 | Contractions | 0 | 1 |
| rth1/rad27 | |||
| CI90 | Expansions | 15 | 4 |
| CI90 | Contractions | 6 | 3 |
| msh2 | |||
| CI90 | Expansions | 2 | 3 |
| CI90 | Contractions (≤2a) | 4 | 7 |
| CI90 | Contractions (≥3a) | 1 | 0 |
| Wild type | |||
| DI97 | Expansions | NA | NA |
| DI97 | Contractions | 1 | 12 |
| rth1/rad27 | |||
| DI97 | Expansions | 16 | 5 |
| DI97 | Contractions | 6 | 9 |
| msh2 | |||
| DI97 | Expansions | 2 | 2 |
| DI97 | Contractions (≤2a) | 11 | 8 |
| DI97 | Contractions (≥3a) | 7 | 9 |
a
Number of repeat units lost.
b
NA, not applicable.