Table 2.
Cox proportional hazards model for the effect of BMI (time-varying) and overweight risk at 9 months of age on islet autoimmunity up to 5.5 years and up to 2.5 years of age
| Risk for islet autoimmunity during follow-up (up to 5.5 years of age) | Risk for early islet autoimmunity (up to 2.5 years of age) | |||||||
|---|---|---|---|---|---|---|---|---|
| N | HR | 95% CI | Adjusted p valuea | N | HR | 95% CI | Adjusted p value* | |
| Time-varying BMI (kg/m2) | 1023 | 1.16 | 1.01, 1.32 | 0.031 | 1023 | 1.14 | 0.98, 1.31 | 0.088 |
| Overweight risk (BMI SDS>1) at 9 months | 1021 | 1.68 | 1.00, 2.82 | 0.048 | 1021 | 1.73 | 0.99, 3.02 | 0.056 |
aAdjusted for first-degree family history of type 1 diabetes, country of residence, sex and whether BMI was assessed during the COVID-19 pandemic