Table 4.
Specific clinical neurological evaluation and laboratory tests for each form of the disease
| Severe forms |
Polysomnography EEG: findings of EEG with epileptiform/aspecific slow-wave abnormalities (even rarer normal EEG patterns) up to severe EEG patterns with burst-suppression or hypsarrhythmia Acute trial with 100 mg IV B6 during EEG recording Brain MRI |
| Moderate formsa |
Standard awake EEG with video recording Neuropsychological evaluation Cognitive-psychological and QoL tests: SF36 [57] FSS test [58] DASS21 test [59] RBANS [60] VAS Pain [61] Other tests as needed (tilt test, ENT, etc.) |
| Mild formsa |
Cognitive-psychological and QoL tests: SF36 [57] FSS test [58] DASS21 test [59] RBANS [60] VAS Pain [61] |
SF36 Short Form 36, FFS Fatigue Severity Scale, DASS21 Depression Anxiety Stress Scales, RBANS Repeatable Battery for the Assessment of Neuropsychological Status, VAS Pain Visual Analogue Scale, ENT Ear Nose Throat examination
aAt the specialist's discretion