Table 1.

Potentially Contraindicated Drugs with Safe Renal Function Cutoffs

Safe Creatinine Clearance	Drugs*
CrClest > 10 mL/min	Acetazolamide, Ifosfamide Methotrexate, Pancuronium, Gold sodium thiomalate, Spironolactone
CrClest > 30 mL/min	Alendronate, choline magnesium salicylate, Demeclocycline, diclofenac, ibuprofen, indomethacin, ketorolac, naproxen, rofecoxib, salsalate, tolmetin
CrClest > 40 mL/min	Sotalol
CrClest > 50 mL/min	Chloral hydrate, Chlorpropamide, Metformin, Nitrofurantoin, Penicillamine, Phenazopyridine, Probenecid, Ribavirin
CrClest > 80 mL/min	Auranofin

^*Medications available on the hospital formulary at the time of the study that were potentially contraindicated owing to renal insufficiency.