Table 1.
Demographics, clinical indications, and outcome of disease in SARS-CoV-2-positive patients.
| Characteristics | All patients (N = 1570) |
Mild (N = 205) |
Hospitalized (N = 760) |
Severe (N = 292) |
Fatal (N = 313) |
p-value |
|---|---|---|---|---|---|---|
| Age - years | 62.0 (49.0 - 76.0) | 47.0 (34.5 - 64.0) | 61.0 (48.3 - 76.0) | 59.0 (50.0 - 70.0) | 71.0 (59.8 - 82.0) | < 0.0001 |
| Male sex | 910 (58.0) | 107 (52.2) | 416 (54.7) | 185 (63.4) | 202 (64.5) | 0.002 |
| Medical History | ||||||
| Diseases of cardiovascular system1 | 547 (34.8) | 11 (5.4) | 257 (33.8) | 111 (38.0) | 168 (53.7) | < 0.0001 |
| Arterial Hypertension | 748 (47.6) | 29 (14.1) | 373 (49.1) | 149 (49.1) | 197 (62.9) | < 0.0001 |
| Diabetes Mellitus | 404 (25.7) | 14 (6.8) | 214 (28.2) | 76 (26.0) | 100 (31.9) | 0.001 |
| Inflammatory markers | ||||||
| Interleukin-6 (high) pg/mL2 | 736 (69.4) | 24 (25.8) | 301 (62.3) | 195 (80.9) | 216 (88.5) | < 0.0001 |
| Procalcitonin (high) ng/mL3 | 779 (57.1) | 16 (15.7) | 291 (42.9) | 205 (73.3) | 267 (87.8) | < 0.0001 |
Classification according to the ECDC COVID-19 surveillance report. Sex and medical history are expressed as absolute number and percentages. All other values are given as median and interquartile range (IQR). Only data that could be obtained from the patients' medical record were included in the calculation. Both pre-existing conditions and laboratory values for IL-6 and PCT were not fully documented; only values that were collected were included in the calculation. Laboratory values were taken at the time of hospital admission, which in the majority of cases corresponded to the early onset of COVID-19.
1e.g. myocardial infarction, coronary heart disease, but not arterial hypertension. 2Interleukin-6 (high) refers to patients in whom the calculated threshold of 18.75 pg/mL was exceeded. 3Procalcitonin (high) refers to patients in whom the calculated threshold of 0.075 ng/mL was exceeded. Units: pg/mL = picogram per milliliter, ng/mL = nanogram per milliliter.