TABLE 11.

Antifungal activity of pyrazole derivatives (4a-j) and pyrazole pyrano[2,3-c]pyrazole derivatives (6a-o).

Strains		Pyrazole derivatives										Drugs		Pyrano[2,3-c]pyrazole derivatives
		4a	4b	4c	4d	4e	4f	4g	4h	4i	4j	A	B	6a	6b	6c	6d	6e	6f	6g	6h	6i	6j	6k	6l	6m	6n	6o
10231	(I)	-	1024	-	4096	2048	1024	2048	1024	512	512	-	32	-	4096	512	-	1024	512	2048	1024	512	1024	512	256	128	128	64
	(II)	-	1024	-	4096	4096	2048	2048	2048	1024	1024	-	64	-	4096	1024	-	2048	1024	2048	2048	512	2048	1024	512	256	256	128
	(III)	-	12.6	-	11.4	11.7	12.1	11.8	13.0	15.9	15.5	-	21.6	-	11.7	16.6	-	12.3	16.9	13.5	14.1	16.3	15.9	16.9	17.8	17.6	17.3	18.4
32045	(I)	-	-	-	-	-	-	-	-	-	-	-	64	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
	(II)	-	-	-	-	-	-	-	-	-	-	-	128	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
	(III)	-	-	-	-	-	-	-	-	-	-	-	17.2	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
7601	(I)	-	-	-	-	-	-	-	-	512	256	-	64	-	-	-	-	-	-	-	-	-	-	-	-	256	256	128
	(II)	-	-	-	-	-	-	-	-	1024	512	-	64	-	-	-	-	-	-	-	-	-	-	-	-	512	256	256
	(III)	-	-	-	-	-	-	-	-	12.7	12.8	-	20.8	-	-	-	-	-	-	-	-	-	-	-	-	13.0	14.6	14.1
1022	(I)	-	512	4096	2048	2048	1024	1024	512	256	256	-	32	2048	-	128	2048	-	64	1024	512	64	512	256	64	16	16	16
	(II)	-	1024	4096	4096	2048	1024	2048	1024	512	256	-	64	4096	-	256	4096	-	128	1024	1024	128	512	512	128	32	32	32
	(III)	-	12.2	14.6	14.8	13.1	13.7	13.8	12.8	15.9	15.5	-	20.3	10.8	-	17.9	11.8	-	18.6	1024	16.3	17.4	17.7	1024	18.2	19.5	19.8	19.3

(I): Minimum Inhibitory Concentration (μg/mL); (II): Minimum Fungicidal Concentration (μg/mL); (III): Inhibition Zone Diameter (mm);

A, tolnaftate; B, terbinafine.