TABLE 3.
Information on synthesized pyrazole derivatives using choline chloride/urea as green method.
| Product code | R1 | R2 | Product structure | Reported Mp (°C) | Found Mp (°C) | Synthesis time (min) | Yield (%) |
|---|---|---|---|---|---|---|---|
| 4a | Ph | Ph |
|
158-159 (Poonam and Singh, 2019) | 159-160 | 20 | 97 |
| 4b | Ph | 2,4-NO2-Ph |
|
240-142 (Bakhtiarian and Khodaei, 2022) | 240-243 | 95 | |
| 4c | 4-Me-Ph | Ph |
|
119-121 (Nemati et al., 2021) | 120-121 | 97 | |
| 4d | 4-Me-Ph | 2,4-NO2-Ph |
|
New | 245-247 | 85 | |
| 4e | 4-OMe-Ph | Ph |
|
107-109 (Abshirini et al., 2020) | 108-110 | 98 | |
| 4f | 4-OMe-Ph | 2,4-NO2-Ph |
|
New | 264-267 | 86 | |
| 4g | 4-NO2-Ph | Ph |
|
165-168 (Nemati et al., 2021) | 166-168 | 97 | |
| 4 h | 4-NO2-Ph | 2,4-NO2-Ph |
|
New | 266-268 | 84 | |
| 4i | 4-Cl-Ph | Ph |
|
128-130 (Amirnejat et al., 2020) | 129-131 | 98 | |
| 4j | 4-Cl-Ph | 2,4-NO2-Ph |
|
234-236 (Aryan et al., 2017) | 235-236 | 93 |
Choline chloride:urea (1: 2); 80°C.