TABLE 9.

Antibacterial activity of pyrazole derivatives (4a-j) and pyrazole pyrano[2,3-c]pyrazole derivatives (6a-o) against gram-negative strains.

Strains		Pyrazole derivatives										Drugs		Pyrano[2,3-c]pyrazole derivatives
		4a	4b	4c	4d	4e	4f	4g	4h	4i	4j	A	B	6a	6b	6c	6d	6e	6f	6g	6h	6i	6j	6k	6l	6m	6n	6o
9610	(I)	-	-	-	-	-	-	-	-	-	-	-	64	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
	(II)	-	-	-	-	-	-	-	-	-	-	-	128	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
	(III)	-	-	-	-	-	-	-	-	-	-	-	12.0	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
13313	(I)	-	-	-	-	-	-	-	-	1024	1024	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1024	512	512
	(II)	-	-	-	-	-	-	-	-	4096	2048	-	-	-	-	-	-	-	-	-	-	-	-	-	-	1024	1024	512
	(III)	-	-	-	-	-	-	-	-	10.7	12.5	-	-	-	-	-	-	-	-	-	-	-	-	-	-	13.6	12.4	12.3
15442	(I)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	2048	-	-	2048	4096	2048	1024	1024	1024	512	512	256	128
	(II)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	4096	-	-	2048	4096	4096	1024	2048	2048	1024	512	256	256
	(III)	-	-	-	-	-	-	-	-	-	-	-	-	-	-	11.8	-	-	11.2	10.1	11.4	12.3	11.9	11.5	12.4	13.6	13.8	13.5
19606	(I)	-	-	-	-	-	-	-	-	-	1024	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	256
	(II)	-	-	-	-	-	-	-	-	-	2048	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	512
	(III)	-	-	-	-	-	-	-	-	-	11.5	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	12.3

(I): Minimum Inhibitory Concentration (μg/mL); (II): Minimum Bactericidal Concentration (μg/mL); (III): Inhibition Zone Diameter (mm);

A, penicillin; B, cefazolin.