Table 2.

Minimum inhibitory concentrations in MHB of a panel of antibiotics and those of their combinations with PDSTP against Pseudomonas aeruginosa PA01 and respective fold reduction.

Pseudomonas aeruginosa PA01	Susceptible (S)	Intermediate (I)	Resistant (R)	MIC	MIC antibiotic + PDSTP	Fold reduction
Amikacin	≤ 16 μg/mL	32 μg/mL	≥ 64 μg/mL	4 μg/mL (S)	1 μg/mL (S)	4x
Tobramycin	≤ 4 μg/mL	8 μg/mL	≥ 16 μg/mL	0.5 μg/mL (S)	0.25 μg/mL (S)	2x
Ceftazidime	≤ 8 μg/mL	16 μg/mL	≥ 32 μg/mL	2 μg/mL (S)	0.0156 μg/mL (S)	128x
Meropenem	≤ 2 μg/mL	4 μg/mL	≥ 8 μg/mL	1 μg/mL (S)	0.0625 μg/mL (S)	16x
Ciprofloxacin	≤ 0.5 μg/mL	1 μg/mL	≥ 2 μg/mL	0.125 μg/mL (S)	0.0078 μg/mL (S)	16x
Colistin	-	≤ 2 μg/mL	≥ 4 μg/mL	1 μg/mL (I)	0.0625 μg/mL (I)	16x

MIC breakpoints used to categorize Pseudomonas aeruginosa as susceptible, intermediate or resistant to antibiotics are shown. Susceptible (S), intermediate (I) and resistant (R) antibiotic profile are indicated below the respective MIC value.