Table 2.
The diagnosis performance of adjusted PI-RADS in predicting csPCa of three different level radiologists in the internal testing cohort and external testing cohorts of center 3 and center 4
| Internal testing cohort | External testing cohort (center 3, CSH) | External testing cohort (center 4, TZH) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adjusted_PI-RADSjunior | 0.884 (0.845–0.923) | 92.3 (96/104) | 70.0 (156/223) | 58.9 (96/163) | 95.1 (156/164) | 0.836 (0.778–0.893) | 92.3 (60/65) | 57.5 (123/214) | 39.7 (60/151) | 96.1 (123/128) | 0.876 (0.831–0.921) | 84.2 (101/120) | 85.2 (109/128) | 84.2 (101/120) | 85.2 (109/128) |
| Adjusted_PI-RADSsenior | 0.891 (0.853–0.930) | 91.3 (95/104) | 74.4 (166/223) | 62.5 (95/152) | 94.9 (166/175) | 0.860 (0.812–0.908) | 76.9 (50/65) | 82.2 (176/214) | 56.8 (50/88) | 92.1 (176/191) | 0.886 (0.843–0.929) | 84.2 (101/120) | 86.7 (111/128) | 85.6 (101/118) | 85.4 (111/130) |
| Adjusted_PI-RADSexpert | 0.902 (0.867–0.938) | 94.2 (98/104) | 72.6 (162/223) | 61.6 (98/159) | 96.4 (162/168) | 0.883 (0.839–0.927) | 92.3 (60/65) | 79.9 (171/214) | 58.2 (60/103) | 97.2 (171/176) | 0.892 (0.849–0.935) | 81.7 (98/120) | 88.3 (113/128) | 86.7 (98/113) | 83.7 (113/135) |
Notes: ROC Receiver operating characteristics, AUC Area under ROC curve, ACC Accuracy, SEN Sensitivity, SPE Specificity, PPV Positive predictive value, NPV Negative predictive value, center 3, CSH Changshu NO.1 People’s Hospital, center 4, TZH People’s Hospital of Taizhou, csPCa Clinically significant prostate cancer, PI-RADS Prostate Imaging Reporting and Data System