TABLE 1.
Quantitation of the extent of acetylation of the individual core histones
No. of acetyl groups/histone | Avg % of total acetates (by wt) for each histonea:
|
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
H2A
|
H2B
|
H3
|
H4
|
|||||||||
U | M | H | U | M | H | U | M | H | U | M | H | |
0 | ndb | nd | nd | 73 | 41 | 16 | 66 | 43 | 20 | 98 | 51 | 24 |
1 | nd | nd | nd | 27 | 32 | 21 | 27 | 23 | 21 | nd | 35 | 33 |
2 | nd | 27 | 28 | 7 | 22 | 28 | nd | 9 | 24 | |||
3 | nd | nd | 35 | nd | 9 | 21 | nd | 5 | 15 | |||
4 | nd | nd | nd | nd | 3 | 10 | 2 | nd | 5 |
U, underacetylated octamer; M, moderately acetylated octamer; H, highly acetylated octamer.
nd, not detected.