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Heatmap of grade 3–5 toxicity spectra based on each of the specific adverse events for multidisciplinary treatment in advanced hepatocellular carcinoma with PVTT. (A) Hematology SAE. (B) Non-hematology SAE. Abbreviations: Ate+Bev, atezolizumab–bevacizumab; HAIC-FO, hepatic arterial infusion chemotherapy plus FOLFOX; HAIC-Cis+Sor, HAIC (cisplatin+5Fu or cisplatin) plus sorafenib; Dur, durvalumab; RT, radiotherapy. The deep color presented a higher risk.
