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. 2023 Oct 18;57(3):e13560. doi: 10.1111/cpr.13560

FIGURE 3.

FIGURE 3

Overexpression of CCL2 promotes the metastasis of NSCLC cells in vivo. (A) CCL2, E‐cadherin and vimentin proteins were detected by IHC in the tissues of NSCLC patients with low metastasis and high metastasis. (B) Gross view of the lungs in the four groups of nude mice with or without metastatic nodules. (C) Statistical graph of lung metastatic nodules in the four groups of nude mice (n = 3, unpaired t‐test; **p < 0.01; ***p < 0.001). (D) H&E and IHC staining of nude mouse lungs. NSCLC, non‐small cell lung cancer.