Figure 3.

Analysis Related to CD8+ Cells. A. t-SNE dimensionality reduction clustering of T cells. B. UMAP dimensionality reduction clustering of T cells. C. Marker genes of T cells. D. Subgroup annotation of T cells. E. Pseudo-temporal analysis of AGG genes in CD8+ cells. F. Cellular trajectory of CD8+ cells. G. NMF clustering of CD8+ cells based on the expression of AGG genes. H. Annotation of AGG clusters after dimensionality reduction of CD8+ cells. I. Communication between AGG clusters and Epithelial cells. J. Global communication between AGG clusters and Epithelial cells. K. Interaction intensity related to receptor pairing between AGG clusters and Epithelial cells. L. Distribution of transcription factors in AGG clusters. M. Distribution of TME genes in AGG clusters. N. Types of T cells in AGG clusters.