Table 1.

Mendelian Randomization Validation of Maker Genes in AGG-Related Clusters

AGG_celltype	Exposure	Method	Nsnp	β	Se	Pval	Lo_ci	Up_ci	Or	Or_lci95	0r_uci95
VIM+CD8+T_cells-C0	SCML4	IVW	3	0.0007	0.0003	0.0184	0.0001	0.0013	1.0007	1.0001	1.0013
VIM+CD8+T_cells-C0	HNRNPF	IVW	3	0.0004	0.0002	0.0155	0.0001	0.0008	1.0004	1.0001	1.0008
UBB+Mac-C2	IFRD1	IVW	6	0.0004	0.0002	0.0255	0	0.0007	1.0004	1	1.0007
TUBA1B+Mac-C0	CTSZ	IVW	3	0.0006	0.0003	0.042	0	0.0012	1.0006	1	1.0012
TUBA1B+Mac-C0	CTSC	IVW	7	-0.0023	0.001	0.0268	-0.0043	-0.0003	0.9977	0.9957	0.9997
TUBA1B+Mac-C0	DAD1	IVW	2	0.0007	0.0003	0.0282	0.0001	0.0014	1.0007	1.0001	1.0014
TUBA1B+Mac-C0	COLEC12	IVW	7	0.001	0.0003	0.1095	0.0003	0.0016	1.001	1.0003	1.0016
TUBA1B+Mac-C0	C2	IVW	2	0.0005	0.0002	0.0181	0.0001	0.0009	1.0005	1.0001	1.0009
TUBA1B+Mac-C0	ATOX1	IVW	2	0.0005	0.0002	0.0596	0.0001	0.0009	1.0005	1.0001	1.0009
Non-Aggre-Mac-C1	CSTA	IVW	3	0.0016	0.0007	0.2724	0.0002	0.003	1.0016	1.0002	1.003
HSP90AA1+CAF-C1	ABL1	IVW	2	0.0004	0.0002	0.0968	0	0.0008	1.0004	1	1.0008