Table 3. Within control group (pre and post) comparison of HAM-A and WHOQOL-BREF.

Data are presented as mean ± standard deviation (SD).

Correlation coefficients (r) are reported for pre-post comparisons.

P-values are considered significant at p < 0.05.

Effect sizes are reported as Cohen's d for pre-post comparisons.

Variables	Pre/post	Mean ± SD	Correlation	P-value	Effect size
HAM-A	Pre	46.78 ± 4.49	0.887	0.000	3.25
	Post	31.91 ± 4.66
Physical domain QOL	Pre	35.04 ± 5.17	0.534	0.002	3.45
	Post	51.67 ± 4.44
Psychological domain QOL	Pre	26.56 ± 7.39	0.688	0.000	2.75
	Post	46.74 ± 7.31
Social domain QOL	Pre	10.16 ± 9.87	0.479	0.006	3.64
	Post	45.31 ± 9.45
Environmental domain QOL	Pre	12.79 ± 8.71	0.681	0.000	3.69
	Post	46.58 ± 9.57