Table 3.
Multivariable log-binomial regression for the association between body mass index and new-onset of heart failure among Thai patients with hypertension, stratified by blood pressure control for the latest two consecutive visits
| Variables | Control BP | Uncontrol BP | p for interaction | ||
|---|---|---|---|---|---|
| aRR (95% CI)* | p-value | aRR (95% CI)* | p-value | ||
| Body mass index (BMI) | |||||
| Continuous (linear) | 1.10 (1.03–1.17) | 0.007 | 1.09 (1.04–1.14) | < 0.001 | 0.477 |
| Continuous (quadratic) | 1.002 (1.001–1.002) | 0.010 | 1.001 (1.001–1.002) | < 0.001 | 0.763 |
| BMI category, kg/m2 | 0.602 | ||||
| < 18.50 | 0.55 (0.12–2.57) | 0.447 | 1.62 (0.41–6.32) | 0.490 | |
| 18.50–22.99 | Ref. | Ref. | |||
| 23.00–24.99 | 1.22 (0.41–3.68) | 0.720 | 1.04 (0.33–3.29) | 0.948 | |
| 25.00–29.99 | 1.61 (0.62–4.17) | 0.327 | 1.53 (0.59–3.99) | 0.382 | |
| ≥ 30.00 | 4.85 (1.77–13.28) | 0.002 | 3.21 (1.17–8.80) | 0.024 | |
| BMI ≥ 25 kg/m2 | 0.642 | ||||
| No | Ref. | Ref. | |||
| Yes | 2.33 (1.12–4.83) | 0.023 | 1.83 (0.93–3.58) | 0.080 | |
| BMI ≥ 30 kg/m2 | 0.926 | ||||
| No | Ref. | Ref. | |||
| Yes | 4.05 (1.73–9.51) | 0.001 | 2.52 (1.25–5.06) | 0.010 | |
BMI body mass index, BP blood pressure, aRR adjusted Risk Ratio, 95% CI 95% confidence interval
*Multivariable analysis: adjusting for age, sex, health schemes, geographic regions, location of outpatient clinic, type 2 diabetes, dyslipidemia, renal insufficiency, history of ischemic heart disease, smoking status, alcohol use, control blood pressure consecutively two latest visits, and ACEI/ARB use