TABLE 1.
In vitro susceptibility testing and FCY1 profiles of 11 Cryptococcus gattii clinical and veterinery isolates used in this study.
| Strains | Other Collection | Year of | Mating | FCY1 | 5FC MIC | Original | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| ID | numbers | Country | isolation | Source | Serotype | Type | Sequence (5΄ → 3΄) | Mutations | (ug/mL) | Reference |
| B9322 | WM1 1.949 | USA | 2011 | clin | B | alpha | TTGAAGAGTCATTCG | LKSHS | >64 | Ref 13 |
| JS5 | WM10.165 | USA | 2005 | vet | B | alpha | TTGAAGAGTCATTCG | LKSHS | >64 | Ref 12 |
| JS69 | WM10.186 | USA | 2006 | vet | B | alpha | TTGAAGAGTCGTTCG | LKSRS | 0.5 | Ref 14 |
| JS91 | WM11.40 | USA | 2011 | vet | C | a | TTGAAGAGCCGTTCG | LKSRS | 0.5 | Ref 14 |
| JS110 | WM11.139 | USA | 2011 | vet | B | a | TTGAAGAGCCGTTCG | LKSRS | 1 | Ref 12 |
| B8965 | WM11.941 | USA | 2010 | clin | B | a | TTGAAGAGCCGTTCG | LKS RS | 1 | Ref 13 |
| B9151 | WM1 1.945 | USA | 2011 | clin | B | alpha | TTGAAGAGCCGTTCG | LKSRS | 1 | Ref 12 |
| B8260 | WM1 1.937 | USA | 2009 | vet | C | alpha | TTGAAGAGCCGTTCG | LKSRS | 0.5 | Ref 13 |
| B8262 | WM1 1.938 | USA | 1992 | clin | B | alpha | TTGAAGAGICGTTCG | LKSRS | 1 | Ref 15 |
| 07-11763 | WM09.45 | USA | 2007 | vet | B | alpha | TTGAAGAGICGTTCG | LKS RS | 1 | Ref 12 |
| 08-7686 | WM09.47 | USA | 2008 | vet | B | alpha | TTGAAGAGICGTTCG | LKSRS | 0.5 | Ref 12 |