Transmission electron micrograph of negative control group showing A; the normal architecture of nerve fibers. Axons have proper arrangement and thickness of myelin sheaths. B, D & F represent the results after 4 weeks of treatment for groups I, II, and I, respectively, whereas C, E &G represent the results after 8 weeks of treatment for the same groups. Asterisks refer to areas of axon loss and contortion of myelin sheath, arrows to areas of axon shrinkage away from Schwann cells, triangles to myelin sheath splitting, and squares to myelin sheath infolding. Ax, axon; M, myelin sheath; Sc, Schwann cell; Co, collagen. Scale bar 5 μm.