Table 7.

Associations between POP serum concentrations and TSH, serum concentrations at age 12 years according to pubertal status among boys (n = 223)

	TSH (mlU log-transformed)
	Tanner 1-2 for genitalia (n = 74)		Tanner 3 for genitalia (n = 87)		Tanner 4-5 for genitalia (n = 62)
Exposure (µg/L log-transformed)	ß	95% Cl	ß	95% Cl	ß	95% Cl	p int
PCB118	0.130	(−0.120, 0.381)	−0.142	(−0.367, 0.082)	−0.268	(−0.552, 0.017)#	##
PCB138	0.065	(−0.157, 0.286)	−0.205	(−0.423, 0.013)#	−0.214	(−0.469, 0.040)#	#
PCB153	0.045	(−0.138, 0.229)	−0.178	(−0.373, 0.017)#	−0.114	(−0.344, 0.116)	##
PCB180	0.050	(−0.098, 0.197)	−0.125	(−0.277, 0.027)	−0.041	(−0.218, 0.136)	##
HCB	0.054	(−0.381, 0.489)	−0.018	(−0.451, 0.415)	−0.560	(−1.101, −0.018)*
p,p'-DDE p,p'-DDE (T2 vs. T1)	0.100	(−0.178, 0.378)	−0.197	(−0.432, 0.038)#	−0.012	(−0.382, 0.358)
p,p'-DDE (T3 vs. T1)	−0.025	(−0.349, 0.298)	−0.095	(−0.349, 0.159)	−0.086	(−0.476, 0.304)
Beta-HCH	0.037	(−0.147, 0.221)	−0.174	(−0.375, 0.027)#	−0.171	(−0.391, 0.050)
PFOA	0.193	(−0.163, 0.550)	−0.092	(−0.374, 0.190)	−0.158	(−0.562, 0.246)
PFNA	−0.010	(−0.399, 0.378)	−0.083	(−0.393, 0.227)	0.062	(−0.208, 0.333)
PFUdA	−0.048	(−0.254, 0.157)	0.031	(−0.167, 0.230)	−0.127	(−0.376, 0.122)
PFDA	−0.208	(−0.528, 0.113)	−0.025	(−0.249, 0.200)	−0.146	(−0.393, 0.101)
PFHxS	0.233	(−0.051, 0.517)	0.037	(−0.197, 0.271)	−0.090	(−0.403, 0.223)
PFOS	0.152	(−0.074, 0.378)	0.021	(−0.194, 0.236)	−0.249	(−0.482, −0.016)*	*

All models adjusted for parental history of thyroid disease, season and hour of blood drawing; and further adjusted for total lipids for PCBs, HCB, p,p'-DDE, and beta-HCH. p int: p value for interaction term between exposure and Tanner stage. HCB, hexachlorbenzene; p,p'-DDE, dichlorodiphenyldichloroethylene; beta-HCH, beta-hexachlorocyclohexane; PFOA, perfluorooctanoic acid; PFNA, perfluorononanoic acid; PFDA, perfluorodecanoic acid; PFUdA, perfluoroundecanoic acid; PFHxS, perfluorohexane sulfonate; PFOS, perfluorooctane sulfonate.

^##p < 0.2

^#p < 0.1

^*p < 0.05.