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. 2024 Feb 14;16:1340117. doi: 10.3389/fnagi.2024.1340117

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Copyright © 2024 Wang, Chen, Yuan, Liu, Fan, Yang, Zou, Pu and Cai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of HBOT on the protein levels of the AMPK/mTOR pathway. Representative immunoblot bands for m-TOR, p-m-TOR, AMPKα, p-AMPKα in the hippocampal region of the control group and the HBOT group mice are presented (as shown in A). Statistical analyses demonstrated that HBOT increased the level of p-AMPKα and the ratio of p-AMPKα/AMPKα, and decreased the level of p-mTOR and the ratio of p-mTOR/mTOR in the hippocampal region (as shown in B). Similar results were observed when N2a cells were treated with HBOT (C,D). (n = 3/group, *p < 0.05, **p < 0.01, ***p < 0.001).