Table 3.
Results of the Clinical Validation Study. Comparison of Clinical Target Volume and Recurrence Coverage Between Standard Radiotherapy (RT) Plan and Tumor Growth Model (TGM)—Derived Target Delineations With Different Isolines Accounting for CutOff Values for Tumor Cell Density.
| Cutoff Value for Tumor Cell Density | Clinical Target Volume | Recurrence Coverage | ||||
|---|---|---|---|---|---|---|
| Mean Volume Ratio (TGM vs. RT Plan) |
T-Value (Wilcoxon Signed Rank Test) | P-Value (Wilcoxon Signed Rank Test) | Mean Improvement of Recurrence Coverage (TGM vs. RT Plan) |
T-Value (Wilcoxon Signed Rank Test) |
P-Value (Wilcoxon Signed Rank Test) | |
| 0.33 | 1.493 | 90.0 | 0.003 | 5.160% | 5.0 | 0.005 |
| 0.5 | 1.220 | 228.0 | 0.093 | 4.567% | 34.0 | 0.044 |
| 0.66 | 1.011 | 151.0 | 0.094 | 2.461% | 77.0 | 0.469 |
| 0.75 | 0.907 | 106.0 | 0.009 | −0.626% | 92.0 | 0.627 |