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. 2024 Feb 26;70:102511. doi: 10.1016/j.eclinm.2024.102511

Table 3.

Studies reporting possible interventions for preventing post-tuberculosis lung function impairment and their main findings.

First author (year of publication), country, and study design Category of intervention Included interventions Number of participants Main findings
Ando M (2003), Japan, RCT Pulmonary Rehabilitation A 9-week pulmonary rehabilitation program 32 PRP appears to have merit when it is given to patients with post-TBC lung disorders
Grass DD (2014), South Africa, RCT Pulmonary rehabilitation A 6-week home-based pulmonary rehabilitation program that included cardiovascular exercises and walking. 67 PRP showed increasing trends towards lung function, but there was no statistical difference between the intervention and control groups
Jones R (2017), Uganda, RCT Pulmonary rehabilitation A 6-week pulmonary rehabilitation program consisted of exercise and education. 34 PRP was feasible and associated with clinically important improvements in respiratory outcomes, exercise capacity, and quality of life
Singh SM (2018), India, Prospective cohort Pulmonary rehabilitation An 8-week pulmonary rehabilitation program that included exercise and education. 29 Pulmonary function tests trended towards improvement with pulmonary rehabilitation but were not statistically significant
Vashakidze SA (2019), USA, Cross-sectional Adjunctive surgical resection Adjunctive lung surgery 54 Adjunctive surgery was significantly associated with improved lung function test
Xu Z (2021), China, RCT Comprehensive nursing care Comprehensive nursing intervention combined with respiratory functional exercises 150 Comprehensive nursing intervention combined with respiratory functional exercises can significantly improve pulmonary function
Orooj M (2023), India, RCT pulmonary rehabilitation A 4-week pulmonary rehabilitation program comprised of supervised exercise and education 90 Short-term PRP was insufficient to register changes in pulmonary function.
Ahmed S (2020), India, RCT Pulmonary rehabilitation 12-week pulmonary rehabilitation program consisted of exercise training, breath retraining, and education. 62 PRP administered along with treatment improved lung function capacity.
Visca D (2019), Italy, Retrospective cohort Pulmonary rehabilitation 3-week pulmonary rehabilitation programme including nurse training, exercises, relaxation, psychological support and nutritional counselling 43 PRP was effective in improving lung function capacity.