Table 7.

Studies reporting possible interventions for preventing other post-tuberculosis sequelae and their main findings.

First author (year of publication), country, and study design	Type of post-tuberculosis sequelae	Category of intervention	Included interventions	Number of participants	Main findings
Strange JIG (1988), South Africa, RCT	Abnormal cardiac function	Adjuvant steroids therapy	Adjuvant steroids therapy (i.e., prednisolone 5 mg tablets for first 11 weeks)	240	Prednisolone significantly reduced post-TB treatment sequala and corticosteroids can be prescribed in addition to anti-TB chemotherapy in the treatment of TB pericarditis.
Shangase KK (2019), South Africa, Retrospective	Hearing impairment	Early medical intervention	Early medical intervention to reduce the dose or stop treatment with ototoxic drugs, replaced by other drugs such as bedaquiline.	86	Early medical strategies implemented had a significant preventive impact.
Girgis NI (1983), Egypt, RCT	Vision impairment	Adjuvant steroids therapy	Adjunct therapy of dexamethasone was given (intramuscular 8–12 mg/day) for the first three weeks of therapy.	55	Dexamethasone does not affect the overall mortality from TBM but appears to prevent the development of severe ocular complications.
Schoeman JF (1997), South Africa, RCT	Vision and hearing impairment	Adjuvant steroids therapy	High-dose prednisone as adjuvant steroids (i.e., corticosteroids) therapy	117	No significant difference was found in the incidence of blindness or deafness between the steroid and nonsteroid groups.