Table 2.

Associations between treelet component scores and colorectal cancer in the EPIC cohort.

Treelet components	OR	95% CI	p-value
TC1	0.93	(0.88–0.99)	0.016
TC2	0.95	(0.90–1.00)	0.053
TC3	0.97	(0.91–1.03)	0.28
TC4	0.96	(0.87–1.04)	0.32
TC5	0.96	(0.88–1.05)	0.35

CI, confidence interval; OR, odds ratio; TC, treelet component.

Estimates obtained from multivariable conditional logistic regression models for the association between each treelet component and colorectal cancer risk, conditioned on matching variables (study centre, sex, age at blood collection, follow-up time since blood collection, time of day and fasting status at blood collection, menopausal status [women], phase of menstrual cycle [pre-menopausal women only] and current use of exogenous hormones [women] and adjusted for baseline measurements of education level (no schooling/primary, secondary/professional/technical, university/higher, not specified/missing), Cambridge physical activity index (inactive, moderately inactive, moderately active, active, unknown), smoking status (never, former, current, unknown), height (cm, continuous), body mass index (kg/m², continuous), alcohol use at recruitment (g/day, continuous), energy intake (kcal/day, continuous), red and processed meat consumption (g/day, continuous), dairy intake (g/day, continuous) and fibre intake (g/day, continuous).