Table 4.
Univariate analysis. Comparing transfusion therapy in women with severe PPH stratified by mode of birth between France and the Netherlands (2011–2013).
| Vaginal birth |
Cesarean birth |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| France N = 214 |
The Netherlands N = 1002 |
France N = 270 |
The Netherlands N = 342 |
|||||||
| n | (%) | n | (%) | P-value | n | (%) | n | %) | P-value | |
| Volume replacement therapy Crystalloids Colloids Crystalloids and colloids |
198 19 19 158 |
(92.5) (9.1) (9.4) (74.0) |
960 95 49 816 |
(95.8) (9.5) (4.9) (81.4) |
0.04 | 250 30 4 216 |
(92.5) (11.1) (1.4) (80.0) |
303 27 0 276 |
(88,6) (7.8) 0 (80,8) |
0.07 |
| Blood transfusion | ||||||||||
| Red blood cells Number of units1 |
214 4 |
(100,0) (3–7) |
1002 4 |
(100.0) (3–5) |
1 | 270 5 |
(100.0) (3–7) |
342 4 |
(100.0) (3–6) |
1 |
| Fresh frozen plasma Number of units1 |
196 2 |
(92.5) (2–4) |
876 2 |
(87.4) (2–3) |
0.04 | 243 4 |
(90.0) (2–6) |
301 2 |
(88.9) (2–5) |
0.91 |
| Thrombocytes Number of units1 |
44 1 |
(20.9) (1–2) |
185 1 |
(18.5) (1–2) |
0.4 | 64 1 |
(23.7) (1–3) |
110 1 |
(32.8) (1–2) |
0.01 |
| Hemostatic agents | ||||||||||
| Fibrinogen | 105 | (49.5) | 83 | (8.3) | < 0.001 | 150 | (55.6) | 47 | (13.7) | < 0.001 |
| Tranexamic acid |
119 | (55.6) | 428 | (42.7) | < 0.001 | 140 | (52.3) | 167 | (50.1) | 0.51 |
| Factor VII | 14 | (6.5) | 23 | (2.3) | < 0.001 | 6 | (2.2) | 14 | (6.5) | 0.23 |
| Time between PPH2 diagnosis and start blood transfusion (median (IQR3)) (minutes) | 95 | (48–159) | 95 | (60–162) | 0.94 | 73 | (26–199) | 80 | (35–130) | 0.35 |
1 among those who were transfused, 2 postpartum hemorrhage, 3 inter quartile range.