Table 5.
Univariate analysis. Comparing second-line therapy and uterine-sparing interventions in women with severe PPH stratified by mode of birth between France and the Netherlands (2011–2013).
| Vaginal birth |
Cesarean birth |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
France |
The Netherlands |
France |
The Netherlands |
|||||||
| N = 214 | N = 1002 | N = 270 | N = 342 | |||||||
| Second-line uterotonics | N | (%) | N | (%) | P-value | N | (%) | N | (%) | P-value |
| Administered Ergot alkaloids Sulprostone Misoprostol |
187 0 178 9 |
(87.3) (0.0) (83.1) (4.2) |
826 99 679 408 |
(82,4) (9,9) (67,7) (40,7) |
0.03 | 192 0 190 2 |
(71.1) (0,0) (70.3) (0.7) |
236 28 221 83 |
(69.0) (8.2) (64.6) (24.2) |
0.35 |
| Time PPH1 diagnosis - second-line uterotonics (median (IQR2)) (minutes) | 25 | (15–45) | 46 | (17–90) | < 0.001 | 18 | (8–45) | 45 | (12–113) | <0.001 |
| Uterine sparing interventions | ||||||||||
| Women with any uterine-sparing intervention | 134 | (62.6) | 394 | (39.3) | < 0.001 | 155 | (57.4) | 133 | (38.9) | <0.001 |
| Multiple uterine-sparing interventions | 28 | (13.1) | 85 | (8.4) | 0.03 | 23 | (8.5) | 37 | (10.8) | 0.30 |
| Intra uterine tamponade | 86 | (40.2) | 347 | (34.6) | 0.12 | 28 | (10.4) | 86 | (25.2) | <0.001 |
| Uterine compression sutures / vascular ligation | 30 | (14.1) | 16 | (1.6) | < 0.001 | 107 | (39.6) | 27 | (7.9) | <0.001 |
| Embolization | 46 | (21.5) | 116 | (11.6) | < 0.001 | 43 | (15.9) | 57 | (16.7) | 0.89 |
1
postpartum hemorrhage; 2 inter quartile range.