HOXC6 promotes invasion and immunosuppression of colon cancer cell lines. (A-B) Alterations in cell migration as well as invasive capacity after inhibition of HOXC6 expression in SW480 and SW620 cell lines. (C-G) The expression levels of CXCL1, CXCL8, IL1β, IL4 and IL10 in SW480 cell line were detected by qRT-PCR before and after HOXC6 inhibition. (H-L) The expression levels of CXCL1, CXCL8, IL1β, IL4 and IL10 in SW620 cell line were detected by qRT-PCR before and after HOXC6 inhibition. N = 3. *≤0.05, **≤0.01, ***≤0.001, ****≤0.0001. N = 6/3, The results are presented as mean ± SD.