Figure 5.

Example calcium traces from awake and anesthetized recordings

(A) Average projection of an episode of quiet wakefulness (QW, left) and during locomotion (loco, right) for the same field of view (FOV) for a healthy wild type mouse (WT). Images reproduced from Pilotto et al., 2023.

(B) Exemplary calcium traces of selected molecular layer interneurons (MLIN, magenta), Golgi cells (Gol, yellow) and Purkinje neurons (PN, gray) in a feedback session (fb) and in darkness in a WT mouse. Shaded gray areas indicate periods of locomotion.

(C) Same as in (A) for a Sca1 mouse.

(D) Same as in (B) for a Sca1 mouse.

(E) Representative anesthetized example traces of all 3 cell types in a WT mouse.

(F) Same as in (E) for a Sca1 mouse. Scale bar in (A) 100 μm, scale is consistent across images. Dashed lines in (A) and (B) delineate cerebellar cortex layers, ML, Molecular layer; PNL, Purkinje neuron layer; GCL, Granular cell layer.