Fig. 2.

Thiohalocapsa PB-PSB1 has nine DGR loci spread across its 7.95 Mb circular, metagenome-assembled genome (A). Loci were categorized according to the maximum likelihood phylogeny of their reverse transcriptase genes (RaxML v8.2.11, BLOSUM62+gamma; 100 rapid bootstraps) (B), and matching template-variable repeats. The four distinct classes are indicated by blue boxes in (C) where each DGR locus is shown with annotated domains for target proteins. Colors scheme corresponds to Fig. 1A. Domain abbreviations include: C-terminal lectin domain (CLec); transmembrane domain (TM); von Willebrand domain (vWA); NACHT domain (PF05729); nSTAND1 domain (nSTAND1); CHAT domain (PF12770); Toll/interleukin-1 receptor domain (TIR, PF13676); protein kinase domain (Pkinase; PF00069); 3′,5′-cyclic AMP phosphodiesterase (Metallo; PF00149).