Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Feb 14;25(3):512–524. doi: 10.1038/s41590-024-01755-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 8 — (a–c) Analyses of scRNAseq dataset of human colorectal carcinomas (Liu et al.⁴³). Dotplots displaying the top 25 statistically significant outgoing interactions from the macrophages 1 (a), cDC2s (b) or monocytes (c) cell clusters to Treg cell clusters computed with the ICELLNET framework. (d) PCA depicting data from bulk NGS data set from (Magnuson et al.²⁷). Comparison between Treg cells isolated from healthy colon biopsies and tumor tissue from colorectal cancer patients. (e) Dotplots displaying FOXP3 gene expression in IL23R^high (IL23R expression > 0) and IL23R^low(IL23R expression = 0) Treg cells from the human pan cancer T cell atlas (Zheng et al. 2021) and colorectal carcinoma (Liu et al.⁴³) scRNA seq data sets.