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. 2024 Mar 1;20(2):33. doi: 10.1007/s11306-024-02098-y

Table 2.

Summary of statistical findings

Metabolites HIV Controls HIV vs Control
Average relative conc. (µmol/L)  ±  Standard deviation Average relative conc. (µmol/L)  ±  Standard deviation Fold change (< 0.5 or > 2.0) Mann–Whitney U (< 0.1) VIP score (> 1.0) d-value (> 0.5)
3-Hydroxybutyric acid 0.0275  ±  0.0313 0.0881  ±  0.1479 0.31 0.0783 0.556
3-Hydroxyisovaleric acid 0.0017  ±  0.0019 0.0007  ±  0.0004 2.57 0.0078 1.48 0.864
4-Deoxythreonic acid 0.0018  ±  0.0013 0.0006  ±  0.0002 3.91 0.0031 1.98 1.039
D-Ribose 0.0062  ±  0.0030 0.0040  ±  0.0012 0.0116 1.51 2.288
Erythritol 0.0373  ±  0.0272 0.0193  ±  0.0056 0.0031 1.75 1.484
Glyceric acid 0.0201  ±  0.0093 0.0132  ±  0.0048 0.0302 1.40 2.199
Glycerol 0.4890  ±  0.7098 0.1891  ±  0.3843 2.59 1.10 0.532
Lactose 0.0019  ±  0.0019 0.0006  ±  0.0005 12.15 1.67 0.870
Methylphosphonic acid 0.0020  ±  0.0008 0.0014  ±  0.0006 0.0242 1.18 2.390
Myo-Inositol 0.4868  ±  0.4873 0.2632  ±  0.1057 1.11 1.183
Pyroglutamic acid 0.0642  ±  0.0224 0.0484  ±  0.0187 0.0377 1.24 2.538
Ribitol 0.0799  ±  0.0311 0.0475  ±  0.0109 0.0022 2.00 2.459
Ribonic acid 0.0141  ±  0.0094 0.0083  ±  0.0029 0.0193 1.47 1.688
Sorbitol 0.0167  ±  0.0097 0.0096  ±  0.0044 0.0042 1.53 1.665
Threonic acid 0.0433  ±  0.0235 0.0258  ±  0.0086 0.0031 1.65 1.944
Trehalose 0.0038  ±  0.0036 0.0006  ±  0.0006 6.33 0.0031 1.44 0.644
Undecylenic acid 0.0049  ±  0.0006 0.0058  ±  0.0013 0.0113 1.23 4.642
Urea 0.2480  ±  0.2082 0.3759  ±  0.2225 0.0853 1.37 1.539