Table 1b.
Characteristics of the adult population: overall, by underweight status, and analytic sub-samples
| Overall (N=14,8 98) |
Underweight (BMI ≤18.5 kg/m2) |
p-
value * |
Overweight/obese (BMI>25 kg/m2) |
p-
value * |
Analytic sub-samples1 | ||||
|---|---|---|---|---|---|---|---|---|---|
| Yes (n=1,029 ) 6.9% |
No (n=13,86 9) 93.1% |
Yes (n=4,39 7) 29.5% |
No (n=10,501 ) 70.5% |
Program- level (n=6,651) |
Area- level (n=14,613 ) |
||||
| Socio-demographic | |||||||||
| Age, years; mean (SD) | 32.7 (12.4) | 28.7 (10.8) | 33.0 (12.4) | <0.001 | 36.9 (13.27) | 30.72(11.52) | <0.001 | 31.2 (12.3) | 32.7 (12.4) |
| Female, % | 48.0 | 52.4 | 47.8 | 0.611 | 41.4 | 50.8 | <0.001 | 49.4 | 48.1 |
| Race/ethnicity, % | |||||||||
| NH White | 88.8 | 86.9 | 88.9 | 0.003 | 89.3 | 88.5 | 0.117 | 88.8 | 88.8 |
| NH Black | 3.0 | 4.6 | 2.9 | 2.7 | 3.2 | 3.2 | 3.0 | ||
| Other | 2.3 | 3.5 | 2.2 | 2.0 | 2.5 | 2.2 | 2.3 | ||
| Hispanic | 5.8 | 4.9 | 5.9 | 6.0 | 5.8 | 5.8 | 5.8 | ||
| Insurance, % | |||||||||
| Any private | 66.8 | 49.6 | 68.1 | <0.001 | 70.3 | 65.3 | <0.001 | 66.6 | 66.9 |
| Public only/None | 33.2 | 50.4 | 31.9 | 29.7 | 34.7 | 33.4 | 33.1 | ||
| Clinical | |||||||||
| Genotype, % | |||||||||
| F508del heteroz | 44.6 | 49.8 | 44.3 | 0.009 | 35.4 | 48.5 | <0.001 | 46.0 | 44.6 |
| F508del homoz | 41.2 | 38.0 | 41.4 | 46.5 | 38.9 | 40.6 | 41.2 | ||
| Other | 14.2 | 12.2 | 14.3 | 18.1 | 12.6 | 13.4 | 14.2 | ||
| CFTR modulator use, % | 65.9 | 63.9 | 66.0 | 0.133 | 62.3 | 67.3 | <0.001 | 67.8 | 65.9 |
| CFRD, % | 31.9 | 37.5 | 31.5 | <0.001 | 29.5 | 32.7 | <0.001 | 31.3 | 31.9 |
| PERT, % | 84.6 | 92.1 | 84.0 | <0.001 | 73.6 | 89.2 | <0.001 | 86.2 | 84.7 |
| Dietitian consultatio n, % | 91.2 | 94.9 | 90.9 | <0.001 | 89.3 | 91.9 | <0.001 | 90.8 | 91.2 |
| Supplemental feeding, % | 48.0 | 81.2 | 45.5 | <0.001 | 24.7 | 57.7 | <0.001 | 49.5 | 48.0 |
*
Difference between underweight and not-underweight in the overall sample
1
The program-level analytic sub-sample includes patients in the CF Foundation Patient Registry (CFFPR) who receive care in programs that responded to the survey. The area-level analytic sub-sample includes all patients in the CFFPR whose residential zip code was successfully matched to a zip-code food access score.
Age is shown as mean (SD).
BMI=Body Mass Index; CF=cystic fibrosis; CFRD=CF-related diabetes; CFTR= CF transmembrane regulator; NH=Non-Hispanic; PERT=Pancreatic enzyme replacement therapy