Table 2.
Comparisons of genes expression between the three clusters.
| Genes | C1 Elderly mean ± SD (n = 16) | C2 Young aged mean ± SD (n = 68) | C3 Young mean ± SD (n = 45) | Statistic | p valuea | Pairwise comparisonsb |
|---|---|---|---|---|---|---|
| CD27 | 0.19 ± 0.07 | 0.34 ± 0.29 | 0.43 ± 0.46 | 11.74 | 0.003 |
1 < 2 (p = 0.04) 1 < 3 (p < 0.001) 2 < 3 (p = 0.038) |
| LDHB | 1.28 ± 0.71 | 1.63 ± 0.64 | 1.80 ± 0.68 | 7.11 | 0.029 |
1 = 2 (p = 0.063) 1 < 3 (p = 0.008) 2 = 3 (p = 0.19) |
| LEF1 | 0.31 ± 0.16 | 0.51 ± 0.48 | 0.60 ± 0.48 | 7.63 | 0.022 |
1 = 2 (p = 0.118) 1 < 3 (p = 0.008) 2 = 3 (p = 0.079) |
| LTB | 0.52 ± 0.18 | 0.76 ± 0.42 | 0.74 ± 0.33 | 8.63 | 0.013 |
1 < 2 (p = 0.005) 1 < 3 (p = 0.006) 2 = 3 (p = 0.92) |
| MYC | 0.11 ± 0.05 | 0.20 ± 0.24 | 0.30 ± 0.43 | 10.62 | 0.005 |
1 = 2 (p = 0.091) 1 < 3 (p = 0.002) 2 < 3 (p = 0.027) |
| PIK3IP1 | 0.20 ± 0.10 | 0.30 ± 0.27 | 0.38 ± 0.39 | 7.01 | 0.030 |
1 = 2 (p = 0.230) 1 < 3 (p = 0.015) 2 = 3 (p = 0.053) |
| POT1 | 1.26 ± 0.73 | 1.40 ± 0.66 | 1.67 ± 0.68 | 6.43 | 0.040 |
1 = 2 (p = 0.57) 1 < 3 (p = 0.045) 2 < 3 (p = 0.027) |
| RPS6 | 1.20 ± 0.45 | 1.48 ± 0.44 | 1.53 ± 0.41 | 6.60 | 0.037 |
1 < 2 (p = 0.046) 1 < 3 (p = 0.010) 2 = 3 (p = 0.316) |
aKruskal-Wallis test ; bDunn’s test.