Table 2.

Significantly different immune subsets between disease severity groups.

Immune subset	Variable	Group1	Group2	p.adj	p.adj.signif
IgM-IgD-IgA-IgG- B cell	B#19	Mild	Severe	0.001	**
IgM memory B cell	B#1	Mild	Severe	0.004	**
CD11cdimCD27+ CD24-CD38hi B cell	B#18	Mild	Severe	0.005	**
IgM-IgD-IgA-IgG- B cell	B#19	Moderate	Severe	0.009	**
CCR6hiCD28hi CD4+ Tcm	CD4#17	Mild	Severe	0.012	*
CCR6hiCD28hi CD4+ Tcm	CD4#17	Moderate	Severe	0.012	*
Atypical circulating B2 B cell	B#8	Mild	Moderate	0.012	*
CD11c+CCR5+HLA-DR+ myeloid cell	M#4	Mild	Severe	0.013	*
CD11cdimCD27+CD24−CD38hi B cell	B#18	Moderate	Severe	0.013	*
atypical circulating B2 B cell	B#8	Mild	Severe	0.014	*
CD56dim CX3CR1+ NK cell	IL#10	Mild	Severe	0.025	*
CD14-CD16dim HLA-DR+CD86+ myeloid	M#6	Mild	Severe	0.026	*
CD56dim CX3CR1+ NK cell	IL#10	Moderate	Severe	0.03	*
CCR6dimPD-1dim CD4+ Tem	CD4#3	Mild	Severe	0.03	*
Not assigned	CD4#12	Mild	Moderate	0.044	*
Not assigned	IL#20	Moderate	Severe	0.046	*
Switched memory IgG+ B cell	B#9	Mild	Severe	0.047	*
Switched memory IgG+ B cell	B#9	Moderate	Severe	0.047	*
Translational CD5+ B cell	B#3	Moderate	Severe	0.047	*

*p.adj ≤ 0.05, **p.adj < 0.01.